Nguyen-Ba-Charvet Kim T, Chédotal Alain
CNRS UMR7102, Paris, F-75005, France.
Neuron. 2006 May 18;50(4):519-21. doi: 10.1016/j.neuron.2006.05.002.
Binocular vision relies upon the existence of contralateral and ispilateral projections from retinal ganglion cells. Contacts between visual axons and optic chiasm cells are critical for the sorting of crossed and uncrossed projections during development. In this issue of Neuron, a study by Williams et al. shows that the cell adhesion molecule Nr-CAM facilitates/promotes the decussation of contralateral axons across the chiasm.
双眼视觉依赖于视网膜神经节细胞的对侧和同侧投射的存在。在发育过程中,视觉轴突与视交叉细胞之间的接触对于交叉和不交叉投射的分选至关重要。在本期《神经元》杂志中,威廉姆斯等人的一项研究表明,细胞粘附分子Nr-CAM促进对侧轴突穿过视交叉的交叉。