White Patrick
Department of General Practice & Primary Care, Guy's, King's & St. Thomas' School of Medicine, King's College London, 5 Lambeth Walk, London SE11 6SP, London, UK.
Prim Care Respir J. 2004 Mar;13(1):5-8. doi: 10.1016/j.pcrj.2003.11.009.
Spirometry is essential for the diagnosis of chronic obstructive pulmonary disease (COPD). In patients with COPD the decline in lung function is usually so slow that spirometry is unlikely to provide significantly new information more than every 1-2 years. However, it is useful to have an objective measure of lung function in the assessment of acute exacerbations of COPD and in the assessment of treatments. Peak expiratory flow (PEF) has been dismissed by national and international guidelines as an inappropriate test for the assessment of the impact of COPD, but with poor evidence in support of this position. This seems short-sighted since PEF is a reliable and reproducible test and could contribute to the management of COPD in the short term and in support of spirometry. As a result of infection or in response to treatment there may be changes in airway calibre in COPD which could be captured in the consultation by PEF. In a primary care setting spirometry is too time consuming and complex to be provided in the context of normal acute consulting. Furthermore there is no evidence that spirometry provides more information than PEF in the day-to-day management of a patient already diagnosed with COPD using forced expiratory volume in the first second/forced vital capacity (FEV1/FVC). Primary care teams should ensure that their patients have adequate access to high quality spirometry. This can be provided in primary care or in local centres or in hospitals depending on the interest, motivation and resources of primary care teams. In support of spirometry general practitioners (GPs) should then consider using PEF in the day-to-day management of COPD.
肺功能测定对于慢性阻塞性肺疾病(COPD)的诊断至关重要。在COPD患者中,肺功能下降通常非常缓慢,以至于肺功能测定每隔1 - 2年才可能提供显著的新信息。然而,在评估COPD急性加重期和治疗效果时,客观测量肺功能是有用的。呼气峰值流速(PEF)已被国家和国际指南排除在评估COPD影响的合适测试之外,但支持这一立场的证据不足。这似乎目光短浅,因为PEF是一项可靠且可重复的测试,在短期内有助于COPD的管理并辅助肺功能测定。由于感染或对治疗的反应,COPD患者的气道口径可能会发生变化,而这可以通过PEF在会诊时检测到。在基层医疗环境中,肺功能测定耗时且复杂,难以在常规急性会诊中进行。此外,没有证据表明在使用第一秒用力呼气量/用力肺活量(FEV1/FVC)对已确诊COPD的患者进行日常管理时,肺功能测定比PEF能提供更多信息。基层医疗团队应确保其患者能够充分获得高质量的肺功能测定。这可以根据基层医疗团队的兴趣、积极性和资源,在基层医疗、当地中心或医院提供。为了支持肺功能测定,全科医生(GPs)在COPD的日常管理中应考虑使用PEF。