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气流受限疾病患者在基层医疗环境中的病情加重情况及医疗资源利用:PUMA研究

Exacerbations and health care resource utilization in patients with airflow limitation diseases attending a primary care setting: the PUMA study.

作者信息

Montes de Oca Maria, Aguirre Carlos, Lopez Varela Maria Victorina, Laucho-Contreras Maria E, Casas Alejandro, Surmont Filip

机构信息

Service of Pneumology, Hospital Universitario de Caracas, Facultad de Medicina, Universidad Central de Venezuela, Caracas, Venezuela.

Colombian Pneumological Foundation, Bogotá, Colombia.

出版信息

Int J Chron Obstruct Pulmon Dis. 2016 Dec 7;11:3059-3067. doi: 10.2147/COPD.S120776. eCollection 2016.

Abstract

BACKGROUND

COPD, asthma, and asthma-COPD overlap increase health care resource consumption, predominantly because of hospitalization for exacerbations and also increased visits to general practitioners (GPs) or specialists. Little information is available regarding this in the primary care setting.

OBJECTIVES

To describe the prevalence and number of GP and specialist visits for any cause or due to exacerbations in patients with COPD, asthma, and asthma-COPD overlap.

METHODS

COPD was defined as post-bronchodilator forced expiratory volume in 1 second/forced vital capacity (FEV/FVC) ratio <0.70; asthma was defined as prior medical diagnosis, wheezing in the last 12 months, or wheezing plus reversibility (post-bronchodilator FEV or FVC increase ≥200 mL and ≥12%); asthma-COPD overlap was defined as post-bronchodilator FEV/FVC <0.70 plus prior asthma diagnosis. Health care utilization was evaluated as GP and/or specialist visits in the previous year.

RESULTS

Among the 1,743 individuals who completed the questionnaire, 1,540 performed acceptable spirometry. COPD patients had a higher prevalence of any medical visits to any physician versus those without COPD (37.2% vs 21.8%, respectively) and exacerbations doubled the number of visits. The prevalence of any medical visits to any physician was also higher in asthma patients versus those without asthma (wheezing: 47.2% vs 22.7%; medical diagnosis: 54.6% vs 21.6%; wheezing plus reversibility: 46.2% vs 23.8%, respectively). Asthma patients with exacerbations had twice the number of visits versus those without an exacerbation. The number of visits was higher (2.8 times) in asthma-COPD overlap, asthma (1.9 times), or COPD (1.4 times) patients versus those without these respiratory diseases; the number of visits due to exacerbation was also higher (4.9 times) in asthma-COPD overlap, asthma (3.5 times), and COPD (3.8 times) patients.

CONCLUSION

COPD, asthma, and asthma-COPD overlap increase the prevalence of medical visits and, therefore, health care resource utilization. Attempts to reduce health care resource use in these patients require interventions aimed at preventing exacerbations.

摘要

背景

慢性阻塞性肺疾病(COPD)、哮喘以及哮喘-COPD重叠综合征会增加医疗资源的消耗,主要原因是急性加重导致的住院治疗,以及全科医生(GP)或专科医生就诊次数的增加。在基层医疗环境中,关于这方面的信息较少。

目的

描述COPD、哮喘以及哮喘-COPD重叠综合征患者因任何原因或急性加重而进行的全科医生和专科医生就诊的患病率及次数。

方法

COPD定义为支气管扩张剂后1秒用力呼气容积/用力肺活量(FEV₁/FVC)比值<0.70;哮喘定义为既往有医学诊断、过去12个月内有喘息或喘息加可逆性(支气管扩张剂后FEV₁或FVC增加≥200 mL且≥12%);哮喘-COPD重叠综合征定义为支气管扩张剂后FEV₁/FVC<0.70加既往哮喘诊断。医疗服务利用情况通过前一年的全科医生和/或专科医生就诊次数进行评估。

结果

在完成问卷的1743名个体中,1540人进行了可接受的肺功能检查。与无COPD的患者相比(分别为37.2%和21.8%),COPD患者看任何医生的任何医疗就诊患病率更高,急性加重使就诊次数增加一倍。与无哮喘的患者相比(喘息:47.2%对22.7%;医学诊断:54.6%对21.6%;喘息加可逆性:46.2%对23.8%),哮喘患者看任何医生的任何医疗就诊患病率也更高。有急性加重的哮喘患者就诊次数是无急性加重患者的两倍。与无这些呼吸系统疾病的患者相比,哮喘-COPD重叠综合征、哮喘(1.9倍)或COPD(1.4倍)患者的就诊次数更高;哮喘-COPD重叠综合征、哮喘(3.5倍)和COPD(3.8倍)患者因急性加重导致的就诊次数也更高。

结论

COPD、哮喘以及哮喘-COPD重叠综合征增加了医疗就诊的患病率,因此也增加了医疗资源的利用。减少这些患者医疗资源使用的尝试需要采取旨在预防急性加重的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bac3/5153276/db40c1d1d20a/copd-11-3059Fig1.jpg

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