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声门上成形术治疗重度喉软化症相关阻塞性睡眠呼吸暂停综合征的疗效评估

Evaluation of the efficacy of supraglottoplasty in obstructive sleep apnea syndrome associated with severe laryngomalacia.

作者信息

Valera Fabiana Cardoso Pereira, Tamashiro Edwin, de Araújo Marcos M, Sander Heidi H, Küpper Daniel S

机构信息

Department of Ophthalmology, University Hospital, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.

出版信息

Arch Otolaryngol Head Neck Surg. 2006 May;132(5):489-93. doi: 10.1001/archotol.132.5.489.

Abstract

OBJECTIVE

To evaluate the clinical and polysomnographic evolution of patients with severe laryngomalacia who underwent supraglottoplasty.

DESIGN

Retrospective study.

SETTING

University hospital.

PATIENTS

Seven children with severe laryngomalacia.

MAIN OUTCOME MEASURES

The patients were evaluated with a questionnaire given to their parents and with polysomnographic examination before and 3 months after surgery. The clinical data of respiratory and swallowing symptoms as well as the parameters of minimum oxygen saturation and respiratory disturbance index were evaluated after bilateral supraglottoplasty and compared with the preoperative data.

RESULTS

Two patients had pharyngolaryngomalacia and required tracheotomy. Four patients had a marked improvement of respiratory and deglutition symptoms. Polysomnographic data showed a significant improvement in the respiratory disturbance index after surgery (P<.05) but not in the minimum oxygen saturation level. However, this improvement was only partially achieved in 3 patients, in whom there were associated airway or neurologic changes. No serious surgical complications were observed.

CONCLUSION

Supraglottoplasty led to a marked improvement in all 5 patients without pharyngolaryngomalacia, but the 2 patients with pharyngolaryngomalacia required tracheotomy.

摘要

目的

评估接受声门上成形术的重度喉软化症患者的临床及多导睡眠图演变情况。

设计

回顾性研究。

地点

大学医院。

患者

7例重度喉软化症患儿。

主要观察指标

通过向患儿父母发放问卷以及在手术前和术后3个月进行多导睡眠图检查对患者进行评估。在双侧声门上成形术后评估呼吸和吞咽症状的临床数据以及最低氧饱和度和呼吸紊乱指数参数,并与术前数据进行比较。

结果

2例患者患有咽-喉软化症,需要进行气管切开术。4例患者的呼吸和吞咽症状有明显改善。多导睡眠图数据显示术后呼吸紊乱指数有显著改善(P<0.05),但最低氧饱和度水平无改善。然而,3例伴有气道或神经改变的患者仅部分实现了这种改善。未观察到严重的手术并发症。

结论

声门上成形术使所有5例无咽-喉软化症的患者有明显改善,但2例患有咽-喉软化症的患者需要进行气管切开术。

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