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喉软化症手术:一家三级儿科医院的系列研究。

Laryngomalacia surgery: a series from a tertiary pediatric hospital.

出版信息

Braz J Otorhinolaryngol. 2012 Dec;78(6):99-106. doi: 10.5935/1808-8694.20120041.

DOI:10.5935/1808-8694.20120041
PMID:23306576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9446370/
Abstract

UNLABELLED

Laryngomalacia is the condition responsible for 75% of the cases of stridor in children aged up to 30 months, in which there is supraglottic collapse during inhalation. Inspiratory stridor is a characteristic telltale. As many as 20% of the patients are severely affected and require surgery. Supraglottoplasty is the procedure of choice and the presence of comorbidities is the most relevant prognostic factor for surgery success.

OBJECTIVE

To describe a series in a tertiary pediatric hospital, its success rates, and surgery prognostic factors.

METHOD

This retrospective cohort study enrolled 20 patients submitted to supraglottoplasty between July 2007 and May 2011.

RESULTS

Thirteen (65%) patients were males; mean age at the time of the procedure was 6.32 months. Endoscopic examination showed that 12 subjects had combined forms of laryngomalacia, 40% had associated pharyngomalacia, and three also had tracheomalacia. Thirteen subjects had isolated laryngomalacia and seven had gastroesophageal reflux disease. Fifteen (75%) patients underwent aryepiglottic fold resection. After the procedure, eleven patients were asymptomatic and two required tracheostomy. Presence of comorbidities was the strongest predictor of unfavorable postoperative outcome (p = 0.034).

CONCLUSION

Supraglottoplasty is a safe therapeutical procedure for select patients with laryngomalacia.

摘要

背景

先天性喉软化症是导致 30 月龄以下儿童 75%喘鸣的原因,其在吸气时会出现会厌上塌。吸气性喘鸣是其特征性表现。多达 20%的患者病情严重,需要手术。杓会厌皱襞切除术是首选术式,并存疾病是手术成功的最相关预后因素。

目的

描述一家三级儿科医院的病例系列,其成功率及手术预后因素。

方法

本回顾性队列研究纳入了 2007 年 7 月至 2011 年 5 月间接受杓会厌皱襞切除术的 20 例患者。

结果

13 例(65%)患者为男性;手术时的平均年龄为 6.32 个月。内镜检查显示 12 例存在混合性先天性喉软化症,40%存在咽成形术后软化,3 例还存在气管软化。13 例存在单纯性先天性喉软化症,7 例存在胃食管反流病。15 例(75%)患者行杓状软骨后联合切除术。术后,11 例患者无症状,2 例需要行气管切开术。并存疾病是术后不良结局的最强预测因素(p=0.034)。

结论

对于选择的先天性喉软化症患者,杓会厌皱襞切除术是一种安全的治疗方法。

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本文引用的文献

1
Submucosal nerve hypertrophy in congenital laryngomalacia.先天性喉软化症的黏膜下神经肥大。
Laryngoscope. 2011 Mar;121(3):627-9. doi: 10.1002/lary.21360. Epub 2011 Jan 13.
2
Supraglottoplasty outcomes in relation to age and comorbid conditions.声门上成形术的结果与年龄和合并症的关系。
Int J Pediatr Otorhinolaryngol. 2010 Mar;74(3):245-9. doi: 10.1016/j.ijporl.2009.11.012. Epub 2009 Dec 21.
3
Synchronous airway lesions and outcomes in infants with severe laryngomalacia requiring supraglottoplasty.需要声门上成形术的重度喉软化症婴儿的同步气道病变及预后
Arch Otolaryngol Head Neck Surg. 2009 Jul;135(7):647-51. doi: 10.1001/archoto.2009.73.
4
Secondary airway lesions in infants with laryngomalacia.喉软化症婴儿的继发性气道病变
Ann Otol Rhinol Laryngol. 2009 Jan;118(1):37-43. doi: 10.1177/000348940911800107.
5
Supraglottoplasty for laryngomalacia with obstructive sleep apnea.用于治疗伴有阻塞性睡眠呼吸暂停的喉软化症的声门上成形术。
Laryngoscope. 2008 Oct;118(10):1873-7. doi: 10.1097/MLG.0b013e31817e7441.
6
Abnormal sensorimotor integrative function of the larynx in congenital laryngomalacia: a new theory of etiology.先天性喉软化症中喉部异常的感觉运动整合功能:一种新的病因学理论。
Laryngoscope. 2007 Jun;117(6 Pt 2 Suppl 114):1-33. doi: 10.1097/MLG.0b013e31804a5750.
7
Polisomnographic findings on children with laryngopathies.喉病患儿的多导睡眠图检查结果。
Braz J Otorhinolaryngol. 2006 Mar-Apr;72(2):187-92. doi: 10.1016/s1808-8694(15)30054-9.
8
Evaluation of the efficacy of supraglottoplasty in obstructive sleep apnea syndrome associated with severe laryngomalacia.声门上成形术治疗重度喉软化症相关阻塞性睡眠呼吸暂停综合征的疗效评估
Arch Otolaryngol Head Neck Surg. 2006 May;132(5):489-93. doi: 10.1001/archotol.132.5.489.
9
[Treatment laryngomalacia: experience with 22 cases].[喉软化症的治疗:22例经验]
Braz J Otorhinolaryngol. 2005 May-Jun;71(3):330-4. doi: 10.1016/s1808-8694(15)31331-8. Epub 2005 Dec 14.
10
Microdebrider-assisted supraglottoplasty.微型切割器辅助声门上成形术
Int J Pediatr Otorhinolaryngol. 2005 Mar;69(3):305-9. doi: 10.1016/j.ijporl.2004.10.009. Epub 2004 Dec 8.