Tol J, Punt C J A
Department of Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
Neth J Med. 2006 May;64(5):133-5.
In recent years several new local as well as systemic treatment options have become available for patients with advanced colorectal cancer. A survey among Dutch hospitals revealed considerable differences in the use of diagnostic and therapeutic strategies. Radiofrequency ablation is a promising technique that is currently being investigated in a randomised trial. The role of adjuvant chemotherapy in patients with resectable liver metastases and of neoadjuvant chemotherapy in patients with nonresectable liver metastases has not been clearly established yet. The current status of local and systemic treatment options for colorectal cancer liver metastases is reviewed.
近年来，对于晚期结直肠癌患者，已有几种新的局部及全身治疗方案可供选择。一项对荷兰医院的调查显示，在诊断和治疗策略的使用上存在显著差异。射频消融是一种很有前景的技术，目前正在一项随机试验中进行研究。辅助化疗在可切除肝转移患者中的作用以及新辅助化疗在不可切除肝转移患者中的作用尚未明确。本文对结直肠癌肝转移的局部和全身治疗方案的现状进行了综述。
