Tsai Shih-Hung, Peng Yi-Jen, Wang Ning-Chi
Division of Infectious Diseases, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Am J Med Sci. 2006 May;331(5):292-4. doi: 10.1097/00000441-200605000-00013.
Both disseminated candidiasis and pyomyositis are rare and mainly encountered in severely immunocompromised hosts. To our knowledge, Candida albicans related pyomyositis with formation of multiple visceral abscesses in a diabetic nephropathy patient has never previously been reported. A 47-year-old man with diabetic nephropathy and alcoholic liver disease developed disseminated candidiasis, with the initial presentation of pyomyositis. Debridement was performed and intravenous fluconazole commenced. Despite development of a single hepatic and multiple perinephric abscesses, the patient made a full recovery after completion of a 12-week course of intravenous fluconazole therapy. Candida species should be considered a potential pathogen in patients with predisposing factors.
播散性念珠菌病和脓性肌炎均较为罕见,主要见于严重免疫功能低下的宿主。据我们所知,此前从未有过白色念珠菌相关的脓性肌炎在糖尿病肾病患者中形成多个内脏脓肿的报道。一名患有糖尿病肾病和酒精性肝病的47岁男性发生了播散性念珠菌病,最初表现为脓性肌炎。进行了清创术并开始静脉注射氟康唑。尽管出现了单个肝脓肿和多个肾周脓肿,但患者在完成12周的静脉注射氟康唑治疗后完全康复。对于有易感因素的患者,应将念珠菌属视为潜在病原体。