Jeng Bennie H, Millstein Michael E
Cole Eye Institute, Cleveland Clinic Foundation, OH 44195, USA.
Eye Contact Lens. 2006 May;32(3):153-6. doi: 10.1097/01.icl.0000182875.61214.cf.
To report the development of progressive hyperopia and astigmatism resulting from peripheral hypertrophic subepithelial degeneration which was treated with superficial keratectomy of the lesion.
Case report.
A patient with peripheral hypertrophic subepithelial degeneration of both corneas was followed up for a 6-year period. During this time, the patient experienced a slowly progressive increase in hyperopia and astigmatism in both eyes. In the left eye, extension of the degeneration paracentrally resulted in significant hyperopia and astigmatism and a best spectacle-corrected visual acuity of 20/70. Superficial keratectomy was performed and resulted in a dramatic reversal of the hyperopic and astigmatic shift and a best spectacle-corrected visual acuity of 20/30.
Peripheral hypertrophic subepithelial corneal degeneration can result in progressive flattening of the central corneal topography in the involved meridians. This flattening can induce a significant hyperopic and astigmatic shift in refraction. This refractive change can be reversed with superficial keratectomy to remove the degeneration.
报告因周边肥厚性角膜上皮下变性导致的进行性远视和散光，并采用病变表层角膜切除术进行治疗。
病例报告。
一名双眼周边肥厚性角膜上皮下变性患者接受了为期6年的随访。在此期间，患者双眼远视和散光呈缓慢进行性增加。左眼，变性向角膜旁中央扩展导致显著远视和散光，最佳矫正视力为20/70。进行了表层角膜切除术，远视和散光偏移得到显著逆转，最佳矫正视力为20/30。
周边肥厚性角膜上皮下变性可导致受累子午线中央角膜地形图逐渐变平。这种变平可导致显著的远视和散光屈光偏移。这种屈光变化可通过表层角膜切除术去除变性而得到逆转。
