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蜱传脑膜脑炎后出现伴有耳内咔嗒声的症状性腭肌阵挛。

Symptomatic palatal myoclonus with ear click after tick-borne meningoencephalitis.

作者信息

Pogorzelski Robert, Drozdowski Wieslaw, Rogowski Marek

机构信息

Department of Neurology, Medical University of Bialystok, 24 A Sklodowska-Curie Str., 15-267 , Bialystok, Poland.

出版信息

Eur Arch Otorhinolaryngol. 2006 Aug;263(8):711-3. doi: 10.1007/s00405-006-0053-7. Epub 2006 May 16.

Abstract

We present a case of a 39-year-old patient, who was diagnosed and treated for a tick-borne meningoencephalitis. Three months after the treatment he started to complain of annoying, cracks-resembling, rhythmical sounds, coming from the inside of his head to both his ears. Physical examination revealed rhythmical oscillations of the soft palate with a frequency of 100-120 per minute and a clock ticking noise synchronic with the palate tremor. Electromyography revealed continuous motor unit activity at rest in the tensor veli palatini muscle. Palatal myoclonus (PM) as a result of tick-borne meningoencephalitis was diagnosed. Treatment with several medications was started with no effect, then botulinum toxin was administered under EMG guidance to both sides of the patient's soft palate with great improvement. A 5-year follow-up and continuation of botulinum toxin injections with only minor and reversible side effects proved the treatment efficacy and safety. In the article we present a case of symptomatic palatal myoclonus with ear click and shortly discuss its aetiology, types and treatment options. We also stress the efficacy and safety of PM treatment with repetitive injections of botulinum toxin.

摘要

我们报告一例39岁患者,其被诊断为蜱传脑膜脑炎并接受了治疗。治疗三个月后,他开始抱怨头部内部发出恼人的、类似裂纹的有节奏声音,双耳均可听到。体格检查发现软腭有节奏性摆动,频率为每分钟100 - 120次,且伴有与腭部震颤同步的类似时钟滴答声。肌电图显示腭帆张肌在静息状态下有持续的运动单位活动。诊断为蜱传脑膜脑炎所致的腭肌阵挛(PM)。开始使用多种药物治疗均无效,随后在肌电图引导下向患者软腭两侧注射肉毒杆菌毒素,症状有显著改善。5年的随访以及持续注射肉毒杆菌毒素且仅有轻微且可逆的副作用,证明了该治疗的有效性和安全性。在本文中,我们报告一例伴有耳部咔嗒声的症状性腭肌阵挛病例,并简要讨论其病因、类型和治疗选择。我们还强调了重复注射肉毒杆菌毒素治疗腭肌阵挛的有效性和安全性。

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