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肉毒杆菌毒素治疗原发性腭肌阵挛性耳鸣。

Botulinum toxin treatment of essential palatal myoclonus tinnitus.

作者信息

Bryce G E, Morrison M D

机构信息

Division of Otolaryngology, University of British Columbia, Vancouver.

出版信息

J Otolaryngol. 1998 Aug;27(4):213-6.

PMID:9711516
Abstract

OBJECTIVE

The purpose of this study was to review the use of botulinum toxin in the treatment of essential palatal myoclonus tinnitus.

DESIGN

Two case series.

METHOD

Four to 10 units of botulium toxin are injected into the tensor veli palatini muscle. The dose and interval between doses is titrated according to patient symptoms. With bilateral symptoms, injection is alternated between sides at sequential visits.

OUTCOME MEASURES

Relief of tinnitus with cessation of palatal contractions.

RESULTS

Both patients had relief of tinnitus. One patient required ventilation tube placement to relieve aural fullness.

CONCLUSIONS

Tensor veli palatini botulinium toxin injection is an effective treatment for essential palatal myoclonus tinnitus.

摘要

目的

本研究旨在回顾肉毒杆菌毒素在治疗原发性腭肌阵挛性耳鸣中的应用。

设计

两个病例系列。

方法

向腭帆张肌注射4至10单位肉毒杆菌毒素。剂量和给药间隔根据患者症状进行调整。对于双侧症状,在连续就诊时两侧交替注射。

观察指标

耳鸣缓解且腭部收缩停止。

结果

两名患者的耳鸣均得到缓解。一名患者需要放置通气管以缓解耳闷。

结论

腭帆张肌注射肉毒杆菌毒素是治疗原发性腭肌阵挛性耳鸣的有效方法。

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