Foo Jong Yong Abdiel, Lim Chu Sing
Biomedical Engineering Research Centre, Nanyang Technological University, 50 Nanyang Drive, Research Techno Plaza, 6th Storey, XFrontiers Block, Singapore, 637553, Singapore.
J Clin Monit Comput. 2006 Jun;20(3):185-92. doi: 10.1007/s10877-006-9019-y. Epub 2006 May 16.
Pulse transit time (PTT) has shown its potential in relevant cardiovascular and cardiorespiratory studies. However, the use of photoplethysmography (PPG) in PTT measurement can be limited in events of poor peripheral perfusion. Uninterrupted PTT monitoring may also not be achievable when less cooperative patients distribute the PPG probe due to its prominent light source. Hence, there is a need for an alternative method to measure PTT in such incidents.
In this study, the piezoelectric (PIEZO) technique to detect pulsations from a human wrist above the radial artery to estimate PTT is presented. 17 healthy adults (11 male; age range of 21-33 years) were recruited to compare PTT and heart rate (HR) differences between the PPG and PIEZO methods. These time-related derivations were made with respect to an electrocardiogram (ECG).
The timing consistency of the PIEZO transducer shows significant correlations (p < 0.01) to those derived from the ECG and a pulse oximeter. Particularly, there is a high level of agreement of < 1 beat per minute (bpm) difference in HR estimates observed when compared to the two commercial devices in the respective Bland-Altman plots. Comparison of PTT obtained from the PIEZO transducer against the PPG signal shows constantly lower values due to the shorter path length it requires to propagate. A regression equation was formulated to relate the PTT values acquired from both these signals.
Preliminary findings herein suggest that the PIEZO technique can be useful as an alternative for PTT monitoring. This shows promise to be more accommodating for less cooperative patients or those with insufficient peripheral perfusion.
脉搏传输时间(PTT)已在相关心血管和心肺研究中显示出其潜力。然而,在周围灌注不良的情况下,使用光电容积脉搏波描记法(PPG)测量PTT可能会受到限制。当不太配合的患者移动PPG探头时,由于其突出的光源,也可能无法实现不间断的PTT监测。因此,在此类情况下需要一种替代方法来测量PTT。
在本研究中,提出了一种利用压电(PIEZO)技术检测桡动脉上方人手腕处的搏动以估计PTT的方法。招募了17名健康成年人(11名男性;年龄范围为21 - 33岁),比较PPG和PIEZO方法之间的PTT和心率(HR)差异。这些与时间相关的推导是相对于心电图(ECG)进行的。
PIEZO传感器的计时一致性与从ECG和脉搏血氧仪得出的结果显示出显著相关性(p < 0.01)。特别是,在各自的布兰德 - 奥特曼图中,与两种商用设备相比,观察到的HR估计差异每分钟小于1次心跳(bpm),一致性很高。将PIEZO传感器获得的PTT与PPG信号进行比较,由于其传播所需的路径长度较短,显示出的值始终较低。制定了一个回归方程来关联从这两种信号获得的PTT值。
本文的初步研究结果表明,PIEZO技术可作为PTT监测的替代方法。这显示出对于不太配合的患者或周围灌注不足的患者更具适用性。