Weber C H, Krötz M, Hoffmann R-T, Euler E, Heining S, Pfeifer K-J, Reiser M, Linsenmaier U
Institut für klinische Radiologie, LMU München.
Rofo. 2006 Jun;178(6):610-7. doi: 10.1055/s-2006-926726. Epub 2006 May 15.
To compare the technical success and complication rates in CT-guided vertebroplasty and kyphoplasty.
From 2002 - 2005 69 patients (101 vertebrae) were treated with vertebroplasty (n = 82) or kyphoplasty (n = 19) using 4-slice MSCT with CT fluoroscopy as the sole guidance for the procedure. The underlying lesions were osteoporotic fractures in 78 vertebral bodies and 23 vertebral metastases.
Technical success was achieved in all 101 procedures. Post-interventional CT demonstrated asymptomatic cement leakage in 51/101 vertebrae. Kyphoplasty resulted in leakage in 11/19 (57.9 %) and vertebroplasty in 40/82 (48.8 %) procedures. With p = 0.48 (Mann-Whitney Test) there was no significant difference between kyphoplasty and vertebroplasty with respect to the number of cement leakage occurrences. There was one minor complication of an L5 root irritation following radiofrequency ablation and vertebroplasty of a sarcoma metastasis which subsided without treatment after 8 weeks. There was one major complication of intraspinal cement leakage during tumor vertebroplasty causing T5 root compression and requiring laminectomy for cement removal. The overall rate of major complications requiring treatment was 0.99 %.
Vertebroplasty and kyphoplasty can be safely performed using only MSCT fluoroscopy guidance. The rate of major complications is very low. There was a high rate of small asymptomatic cement leakages which may have remained undetected with conventional fluoroscopy (CF). There was no statistically significant advantage for kyphoplasty with respect to cement leakage and the technical success rate.
比较CT引导下椎体成形术和后凸成形术的技术成功率及并发症发生率。
2002年至2005年期间,69例患者(101个椎体)接受了椎体成形术(n = 82)或后凸成形术(n = 19),手术仅采用4层螺旋CT及CT透视进行引导。其中78个椎体为骨质疏松性骨折,23个椎体为椎体转移瘤。
101例手术均取得技术成功。术后CT显示,101个椎体中有51个出现无症状骨水泥渗漏。后凸成形术中有11/19(57.9%)发生渗漏,椎体成形术中有40/82(48.8%)发生渗漏。经曼-惠特尼检验,p = 0.48,后凸成形术和椎体成形术在骨水泥渗漏发生率方面无显著差异。1例肉瘤转移灶在进行射频消融及椎体成形术后出现L5神经根刺激的轻微并发症,8周后未经治疗自行缓解。1例肿瘤椎体成形术中发生椎管内骨水泥渗漏,导致T5神经根受压,需行椎板切除术以清除骨水泥,这是1例严重并发症。需要治疗的严重并发症总发生率为0.99%。
仅采用多层螺旋CT透视引导即可安全地进行椎体成形术和后凸成形术。严重并发症发生率很低。小的无症状骨水泥渗漏发生率较高,传统透视检查(CF)可能无法检测到这些渗漏。后凸成形术在骨水泥渗漏及技术成功率方面无统计学上的显著优势。