Seidenari P, Santin G, Milani P, David A
Fatebenefratelli-Oftalmico Hospital, Milano, Italy.
Eur J Ophthalmol. 2006 Mar-Apr;16(2):295-9. doi: 10.1177/112067210601600216.
To evaluate the efficacy and clinical effects of local retrobulbar anesthesia using ropivacaine in vitreoretinal surgery.
Prospective study. A total of 919 vitreoretinal operations were followed. The operations were divided into three groups, depending on the degree of anesthesia needed. Group A: Vitrectomies with episcleral procedures (208 vitrectomies for detached retina or perforating trauma). Group B: Episcleral procedures only (410 operations for detached retina without vitrectomy). Group C: Vitrectomies without episcleral surgery (301 operations for macular pucker or hole, proliferative diabetic retinopathy, or silicone oil removal). Anesthesia was administered using a 23-gauge Atkinson-type retrobulbar needle, after topical anesthesia. Six mL of the solution containing 7.5 mg ropivacaine/mL were injected into the peribulbar space, and the other 4 mL deeper, into the retrobulbar space. The degree of infiltration of the palpebral region, the motor block in the extrinsic ocular muscles, and pain felt were checked and rated.
Swelling of lids was seen in 885 patients (96%); in 21 (2%) swelling was partial. In 13 patients (1%) there were no signs of infiltration. The motor block was total in 801 (87%) eyes, while 118 (12%) had reduced ocular movements. The degree of anesthesia was as follows, considering the three groups together: no pain = 855 (93%) patients; moderate pain = 44 (4%) patients; very strong pain = 20 (2%) patients. No adverse events or side effects were observed.
Ropivacaine used for retrobulbar-peribulbar combined anesthesia in vitreoretinal surgery showed excellent clinical efficacy as regards analgesia and muscle akinesia.
评估罗哌卡因用于玻璃体视网膜手术局部球后麻醉的疗效及临床效果。
前瞻性研究。共对919例玻璃体视网膜手术进行了随访。根据所需麻醉程度将手术分为三组。A组:行巩膜外手术的玻璃体切除术(208例视网膜脱离或穿通伤的玻璃体切除术)。B组:仅行巩膜外手术(410例未行玻璃体切除术的视网膜脱离手术)。C组:未行巩膜外手术的玻璃体切除术(301例黄斑皱褶或裂孔、增殖性糖尿病视网膜病变或硅油取出手术)。表面麻醉后,使用23号阿特金森型球后针进行麻醉。将6 mL含7.5 mg/mL罗哌卡因的溶液注入球周间隙,另外4 mL注入更深的球后间隙。检查并评估睑裂区浸润程度、眼外肌运动阻滞情况及疼痛感受。
885例患者(96%)出现眼睑肿胀;21例(2%)为局部肿胀。13例患者(1%)无浸润迹象。801只眼(87%)出现完全性运动阻滞,118只眼(12%)眼动减少。综合三组情况,麻醉程度如下:无痛 = 855例患者(93%);中度疼痛 = 44例患者(4%);剧痛 = 20例患者(2%)。未观察到不良事件或副作用。
罗哌卡因用于玻璃体视网膜手术的球后 - 球周联合麻醉在镇痛和肌肉麻痹方面显示出优异的临床疗效。