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囊性纤维化儿童和青少年的6分钟步行试验

Six-minute walk test in children and adolescents with cystic fibrosis.

作者信息

Cunha Maristela Trevisan, Rozov Tatiana, de Oliveira Rosangela Caitano, Jardim José R

机构信息

Pulmonary Rehabilitation Center, Federal University of São Paulo, Rua Botucatu, São Paulo, Brazil.

出版信息

Pediatr Pulmonol. 2006 Jul;41(7):618-22. doi: 10.1002/ppul.20308.

DOI:10.1002/ppul.20308
PMID:16703573
Abstract

The 6-min walk test is a simple, rapid, and low-cost method that determines tolerance to exercise. We examined the reproducibility of the 6-min walk test in 16 children with cystic fibrosis (11 female, 5 male; age range, 11.0 +/- 1.9 years). We related the distance walked and the work performed (distance walked x body weight) with nutritional (body mass index and respiratory muscle strength) and clinical (degree of bronchial obstruction and Shwachman score) status. Patients were asked to walk as far as possible upon verbal command on two occasions. There was no statistical difference between distances walked (582.3 +/- 60 and 598.2 +/- 56.8 m, P = 0.31), heart rate, respiratory rate, pulse oxygen saturation, arterial blood pressure, dyspnea, and percentage of maximal heart rate for age in the two tests. Distance walked correlated (Pearson) with maximal expiratory pressure (98.6 +/- 28.1 cmH2O, r = 0.60, P < 0.01), maximal heart rate (157.9 +/- 10.1 bpm, r = 0.59, P < 0.02), Borg dyspnea scale (1.7 +/- 2.4, r = 0.55, P < 0.03), and double product (blood pressure x heart rate; r = 0.59, P < 0.02). The product of distance walked and body weight (work) correlated (Pearson) with height (r = 0.83, P = 0.000), maximal expiratory pressure (r = 0.64, P < 0.01), systolic blood pressure (r = 0.56, P < 0.02), and diastolic blood pressure (r = 0.55, P < 0.03). We conclude that the 6-min walk test is reproducible and easy to perform in children and adolescents with cystic fibrosis. The distance walked was related to the clinical variables studied. Work in the 6-min walk test may be an additional parameter in the determination of physical capacity.

摘要

6分钟步行试验是一种简单、快速且低成本的运动耐量测定方法。我们对16名囊性纤维化患儿(11名女性,5名男性;年龄范围为11.0±1.9岁)的6分钟步行试验的可重复性进行了研究。我们将步行距离和所做的功(步行距离×体重)与营养状况(体重指数和呼吸肌力量)及临床状况(支气管阻塞程度和舒瓦茨曼评分)进行了关联。要求患者在两次听到口头指令后尽可能远地行走。两次试验中步行距离(582.3±60米和598.2±56.8米,P = 0.31)、心率、呼吸频率、脉搏血氧饱和度、动脉血压、呼吸困难程度以及年龄最大心率百分比之间均无统计学差异。步行距离与最大呼气压力(98.6±28.1厘米水柱,r = 0.60,P < 0.01)、最大心率(157.9±10.1次/分钟,r = 0.59,P < 0.02)、博格呼吸困难量表评分(1.7±2.4,r = 0.55,P < 0.03)以及双乘积(血压×心率;r = 0.59,P < 0.02)相关。步行距离与体重的乘积(功)与身高(r = 0.83,P = 0.000)、最大呼气压力(r = 0.64,P < 0.01)、收缩压(r = 0.56,P < 0.02)和舒张压(r = 0.55,P < 0.03)相关。我们得出结论,6分钟步行试验在囊性纤维化儿童和青少年中具有可重复性且易于实施。步行距离与所研究的临床变量相关。6分钟步行试验中的功可能是确定体能的一个额外参数。

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