Trimethylsilylation of penicillic acid and patulin, and the stability of the products.

Suzuki T, Fujimoto Y, Hoshino Y, Tanaka A

J Chromatogr. 1975 Feb 19;105(1):95-8. doi: 10.1016/s0021-9673(01)81092-x.

Penicillic acid and patulin have been effectively silylated by N,O-bis(trimethylsilyl)acetamide, alone or with trimethylchlorosilane in benzene. The silylation products are stable, if stored under refrigeration, for at least 15 days.