Shanidze G S, Mindadze A A, Kalmakhelidze R A, Kalividze E G, Kvirikashvili T O
Georgian Med News. 2006 Apr(133):14-7.
Gastrointestinal tract and abdominal lymph nodes are common sites for development of lymphosarcomas in children (36-53% of all lymphomas). Lymphosarcoma is a malignant tumor developed from the lymphoid tissue and characterized with broad spectrum of clinical manifestations, inhomogeneous course of the disease and prognosis. 25 (24,0% of all abdominal lymphosarcomas) patients with intestinal lymphosarcoma admitted to the childhood tumors department of the National Cancer Center of Georgia from 1980 to 2006. One of the most informative diagnostic methods for this disease is X-ray examination. Ultrasound and CT are leading investigating methods giving us possibility to determine topography of the tumour as well as to evaluate efficiency of the specific treatment and carry out a dynamic control of the patients after the complete remission. In all patients with intestinal lymphosarcomas surgical treatment without any preoperative specific therapy (chemotherapy, radiotherapy) has been carried out. Analysis of the specific treatment results obtained has shown that intestinal lymphosarcoma is the disease with worse prognosis in comparison with abdominal lymph nodes lymphosarcoma. It has been ascertained that in 88,0% of abdominal lymph node damages complete cure can be achieved using surgery and rational program of ACOP chemotherapy.
胃肠道和腹部淋巴结是儿童淋巴肉瘤常见的发病部位(占所有淋巴瘤的36% - 53%)。淋巴肉瘤是一种起源于淋巴组织的恶性肿瘤,具有广泛的临床表现、疾病进程和预后不均一的特点。1980年至2006年期间,25例(占所有腹部淋巴肉瘤的24.0%)肠道淋巴肉瘤患者入住格鲁吉亚国家癌症中心儿童肿瘤科。X线检查是该疾病最具诊断价值的方法之一。超声和CT是主要的检查方法,可帮助我们确定肿瘤的位置,评估特定治疗的效果,并在完全缓解后对患者进行动态监测。所有肠道淋巴肉瘤患者均接受了手术治疗,未进行任何术前特殊治疗(化疗、放疗)。对所获得的特定治疗结果分析表明,与腹部淋巴结淋巴肉瘤相比,肠道淋巴肉瘤的预后较差。已确定,在88.0%的腹部淋巴结受累病例中,通过手术和合理的ACOP化疗方案可实现完全治愈。