Cantani A
Department of Pediatrics, University of Rome La Sapienza, Italy.
Eur Rev Med Pharmacol Sci. 2006 Mar-Apr;10(2):61-8.
Several elimination diets have been suggested based on results of skin prick tests (SPTs) or IgE antibodies to foods, thus allowing the identification of the most common offending food(s), including CM (cow's milk), egg, peanut and wheat. But unbalanced, inappropriate dietary manipulation in infants with food allergy (FA) can have critically deleterious consequences. We have investigated the effectiveness of a home-made meat-based formula (HMMBF) (Rezza's diet) in babies with food-induced atopic dermatitis (AD), a common, disabling, chronic disease of infancy.
Rezza's diet was given for two months to 25 infants (median age 6.9 months) affected with AD and FA and the differences of body weight and AD severity score were recorded before and after the diet period. Data were analysed using the T and c2 tests.
There was a significant improvement in both the evaluated parameters, whereas in 26 control atopic babies they remained unchanged.
The results of our study indicate that the HMMBF, also based on the experience of several authors, is a useful oligoantigenic diet for the treatment of food-induced AD, and the prevention of the atopic march.
基于皮肤点刺试验(SPT)结果或食物特异性IgE抗体,已提出多种排除饮食法,从而能够确定最常见的致敏食物,包括牛奶、鸡蛋、花生和小麦。但是,对食物过敏(FA)婴儿进行不均衡、不适当的饮食调整可能会产生极其有害的后果。我们研究了一种自制的肉类配方奶粉(HMMBF)(雷扎饮食法)对食物诱导性特应性皮炎(AD)婴儿的有效性,AD是一种常见的、致残的婴儿慢性疾病。
对25名患有AD和FA的婴儿(中位年龄6.9个月)采用雷扎饮食法两个月,记录饮食前后的体重差异和AD严重程度评分。使用T检验和卡方检验分析数据。
两个评估参数均有显著改善,而26名对照特应性婴儿的参数保持不变。
我们的研究结果表明,基于多位作者经验的HMMBF是一种用于治疗食物诱导性AD以及预防特应性进程的有效低抗原性饮食。