Zhang Xizheng, Guo Yong, Li Reixin, Zhao Yunshan, Wu Jimin, Guan Jing
Institute of Military Medical Equipment, Academy Military Medical Sciences, Tianjin 300161, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2006 Apr;23(2):326-8.
Uniaxial stretch strain and compressive pressure of 2 atm were applied to rat's osteoblasts, and then immunohistochemistrical staining was used to detect the expression of osteoblasts' c-fos gene. The experiment result indicated the osteoblasts' FOS proteins increased prominently, and the FOS proteins concentrated in nucleolus after having endured two different kinds of loadings. It is very important to prompt stress and strain in promoting osteoblast proliferation.
对大鼠成骨细胞施加单轴拉伸应变和2个大气压的压缩压力，然后采用免疫组织化学染色法检测成骨细胞c-fos基因的表达。实验结果表明，成骨细胞的FOS蛋白显著增加，且在承受两种不同负荷后FOS蛋白集中在核仁中。在促进成骨细胞增殖方面，快速施加应力和应变非常重要。
