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美国医院中耐药大肠杆菌和克雷伯菌属中的1类整合子。

Class 1 integrons in resistant Escherichia coli and Klebsiella spp., US hospitals.

作者信息

Rao Aarati N, Barlow Miriam, Clark Leigh Ann, Boring John R, Tenover Fred C, McGowan John E

机构信息

Emory University, Atlanta, Georgia 30322, USA.

出版信息

Emerg Infect Dis. 2006 Jun;12(6):1011-4. doi: 10.3201/eid1206.051596.

DOI:10.3201/eid1206.051596
PMID:16707065
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3373057/
Abstract

We examined Escherichia coli and Klebsiella spp. from US hospitals for class 1 integrons. Of 320 isolates, 181 (57%) were positive; association of integrons with resistance varied by drug and organism. Thus, determining integron epidemiology will improve understanding of how antibacterial resistance determinants spread in the United States.

摘要

我们检测了美国医院的大肠杆菌和克雷伯菌属菌株中的1类整合子。在320株分离菌中，181株（57%）呈阳性；整合子与耐药性的关联因药物和菌种而异。因此，确定整合子的流行病学情况将有助于更好地理解抗菌药物耐药决定因素在美国的传播方式。

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Nat Med. 2006 Jan;12(1):83-8. doi: 10.1038/nm1347. Epub 2005 Dec 20.
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Integrons: adding another threat to the use of antibiotic therapy.整合子：给抗生素治疗的应用增添了另一威胁。
Clin Infect Dis. 2005 Jul 1;41(1):10-1. doi: 10.1086/430715. Epub 2005 May 26.
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Integron content of extended-spectrum-beta-lactamase-producing Escherichia coli strains over 12 years in a single hospital in Madrid, Spain.西班牙马德里一家医院12年间产超广谱β-内酰胺酶大肠杆菌菌株的整合子含量
Antimicrob Agents Chemother. 2005 May;49(5):1823-9. doi: 10.1128/AAC.49.5.1823-1829.2005.
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Integrons and gene cassettes in clinical isolates of co-trimoxazole-resistant Gram-negative bacteria.耐复方新诺明革兰氏阴性菌临床分离株中的整合子和基因盒
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Changes in gene cassettes of class 1 integrons among Escherichia coli isolates from urine specimens collected in Korea during the last two decades.过去二十年韩国采集的尿液标本中大肠杆菌分离株1类整合子基因盒的变化
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