Williams Anita E, O'Neill Terence W, Mercer Sylvia, Toro Brigitte, Nester Christopher J
Department of Podiatry, University of Salford, Frederick Road, Salford, England.
J Am Podiatr Med Assoc. 2006 May-Jun;96(3):226-31. doi: 10.7547/0960226.
The characteristic bone deformities associated with advanced Paget's disease of bone may result in abnormal gait and plantar foot pressures, which contribute to the development of pressure-related skin problems. This study aimed to characterize the foot problems and foot-care needs in this patient group and to investigate the effect of disease distribution on the occurrence of foot pathology. One hundred thirty-four patients with Paget's disease were assessed clinically, and the Foot Structure Index was completed for each patient. Patients completed self-administered questionnaires concerning foot function (Foot Function Index) and quality of life (12-Item Short Form). The results of this study suggest that foot-health and footwear problems are common in patients with Paget's disease. Forty percent of the patients required professional foot care in addition to those already receiving it. The site of pagetic involvement did not affect the occurrence of foot pathology. Further research is required on the impact of the extent of any femoral or tibial deformity on foot symptoms and pathology. Biomechanical studies of the forces and motion in the foot related to different degrees of femoral and tibial deformity might also help determine the impact of deformity on foot pathology.
与晚期骨佩吉特病相关的典型骨骼畸形可能导致步态异常和足底压力异常，进而促使与压力相关的皮肤问题的发生。本研究旨在描述该患者群体的足部问题和足部护理需求，并调查疾病分布对足部病变发生的影响。对134例佩吉特病患者进行了临床评估，并为每位患者完成了足部结构指数评估。患者完成了关于足部功能（足部功能指数）和生活质量（12项简表）的自填式问卷。本研究结果表明，足部健康和鞋类问题在佩吉特病患者中很常见。40%的患者除了已接受的护理外，还需要专业足部护理。佩吉特病累及部位不影响足部病变的发生。需要进一步研究股骨或胫骨畸形程度对足部症状和病变的影响。对与不同程度股骨和胫骨畸形相关的足部受力和运动进行生物力学研究，可能也有助于确定畸形对足部病变的影响。
