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[一名4.5岁1型糖尿病女童的潜在性乳糜泻——病例报告]

[Latent coeliac disease in a 4.5-year-old girl with type 1 diabetes mellitus--case report].

作者信息

Szaflarska-Popławska Anna

机构信息

Uniwersytet Mikołaja Kopemika w Toruniu, Collegium Medicum w Bydgoszczy, Katedra i Klinika Pediatrii, Alergologii i Gastroenterologii.

出版信息

Pol Merkur Lekarski. 2006 Feb;20(116):207-9.

PMID:16708642
Abstract

Four and half year-old girl with type I diabetes mellitus and latent coeliac disease was presented. The typical serological screening at type I diabetes mellitus onset was negative. Three years later serological screening was performed again because of recurrent diarrhoea. At the time serum IgA antiendomysial antibody was positive. The intestinal biopsy showed subtotal villous atrophy with intraepithelial lymphocyte infiltration and elongated crypts. It seems that diabetic children should be periodically checked by screening tests for coeliac disease.

摘要

报告了一名患有I型糖尿病和潜在乳糜泻的4岁半女童。I型糖尿病发病时进行的典型血清学筛查为阴性。三年后,由于反复腹泻再次进行血清学筛查。当时血清抗肌内膜IgA抗体呈阳性。肠道活检显示绒毛部分萎缩,伴有上皮内淋巴细胞浸润和隐窝延长。似乎糖尿病儿童应定期通过乳糜泻筛查试验进行检查。

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