Godon Nathalie, Denizot Sophie, Podevin Guillaume, Caillon Jocelyne, Potel Gilles, Christophe Roze Jean, Gras-Le Guen Christele
Réanimation Pédiatrique, Hôpital Mère Enfant, CHU-Nantes, France.
Scand J Infect Dis. 2006;38(5):381-3. doi: 10.1080/00365540500372937.
Two children with severe pneumonia, purulent pleural effusions, and abscess formation unresponsive to appropriate antibiotic therapy recovered promptly after the introduction of linezolid and imipenem association. Linezolid is a new antibiotic with high bioavailability and an outstanding safety profile, synergistic with imipenem, which may deserve a place in the armamentarium for severe pneumonia in children.