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对感染和未感染人类免疫缺陷病毒的同性恋男性进行多学科基线评估。I. 研究设计概述。

Multidisciplinary baseline assessment of homosexual men with and without human immunodeficiency virus infection. I. Overview of study design.

作者信息

Gorman J M, Kertzner R, Todak G, Goetz R R, Williams J B, Rabkin J, Meyer-Bahlburg H F, Mayeux R, Stern Y, Lange M

机构信息

HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, NY.

出版信息

Arch Gen Psychiatry. 1991 Feb;48(2):120-3. doi: 10.1001/archpsyc.1991.01810260028004.

DOI:10.1001/archpsyc.1991.01810260028004
PMID:1671197
Abstract

Although much is known about the virus believed by most experts to be the cause of the acquired immunodeficiency syndrome and about its pathogenic actions, major areas of ignorance remain. Among these are the reasons for the varying time between infection with human immunodeficiency virus and development of acquired immunodeficiency syndrome, the relationship between neurologic and medical aspects of the disease, the time course of neuropsychological findings, and the prevalence of psychiatric morbidity. We assessed 124 homosexual men who were positive for human immunodeficiency virus and 84 who were negative for the virus. In this article we describe the study design, method of recruitment, and medical and demographic characteristics of the cohort, which will be followed up for 5 years.

摘要

尽管大多数专家认为导致获得性免疫缺陷综合征的病毒及其致病作用已为人熟知,但仍存在许多重大未知领域。其中包括感染人类免疫缺陷病毒与患上获得性免疫缺陷综合征之间时间差异的原因、该疾病神经学与医学方面的关系、神经心理学检查结果的时间进程以及精神疾病的患病率。我们评估了124名人类免疫缺陷病毒检测呈阳性的同性恋男性和84名病毒检测呈阴性的男性。在本文中,我们描述了研究设计、招募方法以及该队列的医学和人口统计学特征,该队列将接受为期5年的随访。

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Multidisciplinary baseline assessment of homosexual men with and without human immunodeficiency virus infection. I. Overview of study design.对感染和未感染人类免疫缺陷病毒的同性恋男性进行多学科基线评估。I. 研究设计概述。
Arch Gen Psychiatry. 1991 Feb;48(2):120-3. doi: 10.1001/archpsyc.1991.01810260028004.
2
Multidisciplinary baseline assessment of homosexual men with and without human immunodeficiency virus infection. III. Neurologic and neuropsychological findings.对感染和未感染人类免疫缺陷病毒的同性恋男性进行多学科基线评估。III. 神经学和神经心理学研究结果。
Arch Gen Psychiatry. 1991 Feb;48(2):131-8. doi: 10.1001/archpsyc.1991.01810260039006.
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Multidisciplinary baseline assessment of homosexual men with and without human immunodeficiency virus infection. II. Standardized clinical assessment of current and lifetime psychopathology.
Arch Gen Psychiatry. 1991 Feb;48(2):124-30. doi: 10.1001/archpsyc.1991.01810260032005.
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Depression, distress, lymphocyte subsets, and human immunodeficiency virus symptoms on two occasions in HIV-positive homosexual men.
Arch Gen Psychiatry. 1991 Feb;48(2):111-9. doi: 10.1001/archpsyc.1991.01810260019002.
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A preliminary report on the neuropsychologic sequelae of human immunodeficiency virus.人类免疫缺陷病毒神经心理后遗症的初步报告
Arch Gen Psychiatry. 1991 Feb;48(2):139-42. doi: 10.1001/archpsyc.1991.01810260047007.
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Direct comparison of the relationship between clinical outcome and change in CD4+ lymphocytes in human immunodeficiency virus-positive homosexual men and injecting drug users.人类免疫缺陷病毒阳性同性恋男性和注射吸毒者临床结局与CD4 +淋巴细胞变化之间关系的直接比较。
Arch Intern Med. 1994 Apr 25;154(8):869-75.
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Glucocorticoid level and neuropsychiatric symptoms in homosexual men with HIV infection.感染HIV的同性恋男性的糖皮质激素水平与神经精神症状
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The immunological and clinical outcome of HIV infection: 31 months of follow-up in a cohort of homosexual men.HIV感染的免疫学和临床结果:对一组同性恋男性进行31个月的随访
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