Jahn Thomas, Cohen Rudolf, Hubmann Werner, Mohr Fritz, Köhler Iris, Schlenker Regine, Niethammer Rainer, Schröder Johannes
Department of Psychiatry and Psychotherapy, Technical University Munich, Germany.
Psychiatry Res. 2006 Jun 15;142(2-3):177-89. doi: 10.1016/j.psychres.2002.12.002. Epub 2006 May 19.
Subtle motor impairment is an important aspect of neurological soft signs (NSS) which are frequently found in psychiatric patients-particularly schizophrenic patients. On the basis of data collected in previous studies using two different NSS scales, the most reliable and discriminative signs of motor impairment were identified to construct a brief 10-item rating scale. Subsequently, the new scale was applied to a sample of subacute patients with schizophrenic psychoses (N = 82) and healthy controls (N = 33). Factor analysis identified two factors which were labeled "motor coordination" and "motor sequencing". Both the total score and the subscores showed high internal consistency and test-retest reliability. There were highly significant group differences on the total score and the subscores as well as on each individual task. The scale has high sensitivity (84.1%) and specificity (87.9%) indicating that it may provide an effective instrument for the screening of subjects with neurodysfunction as well as for monitoring motor dysfunction in the clinical course of psychiatric disorders.
细微运动障碍是神经软体征（NSS）的一个重要方面，在精神科患者尤其是精神分裂症患者中经常出现。基于以往使用两种不同NSS量表收集的数据，确定了最可靠且具有鉴别力的运动障碍体征，以构建一个简短的10项评定量表。随后，将新量表应用于亚急性精神分裂症性精神病患者样本（N = 82）和健康对照样本（N = 33）。因子分析确定了两个因子，分别标记为“运动协调”和“运动序列”。总分和各子分数均显示出高内部一致性和重测信度。在总分、子分数以及每个单独任务上，组间差异均极为显著。该量表具有高敏感性（84.1%）和特异性（87.9%），表明它可能为筛查神经功能障碍患者以及监测精神疾病临床过程中的运动功能障碍提供一种有效的工具。
