Tseng Hung-Fu, Tan Hsiu-Fen, Chang Chen-Kang
Institute of Medical Research, Chang-Jung Christian University, 396, Sec. l, Chang Jung Rd, Kway Jen, Tainan 711, Taiwan, ROC.
Vaccine. 2006 Jun 19;24(25):5341-8. doi: 10.1016/j.vaccine.2006.04.025. Epub 2006 May 2.
The aims of this study were to investigate the epidemiology of varicella and evaluate the effect of varicella vaccination on the burden of varicella in Taiwan. The outpatient and hospitalization claims made to the National Health Insurance (NHI) in public and private vaccination areas were compared during 2000-2002. In 2002, the outpatient visit rates for 1- to 5-year-old children in public vaccination areas were 66-78% lower than their counterparts in private vaccination areas. The reduction in outpatient visit rate was the greatest among preschool children. The reductions also occurred in every age group including infants and adults. This study showed significant evidence of vaccine impact with a marked decline in clinical cases in the short term.
本研究的目的是调查水痘的流行病学情况，并评估水痘疫苗对台湾地区水痘负担的影响。对2000年至2002年期间公立和私立疫苗接种地区向国民健康保险（NHI）提出的门诊和住院理赔申请进行了比较。2002年，公立疫苗接种地区1至5岁儿童的门诊就诊率比私立疫苗接种地区的同龄人低66%至78%。门诊就诊率的下降在学龄前儿童中最为明显。各年龄组包括婴儿和成人也出现了下降。这项研究显示了疫苗影响的显著证据，短期内临床病例显著减少。
