Kwong Jeffrey C, Tanuseputro Peter, Zagorski Brandon, Moineddin Rahim, Chan Kevin J
Institute for Clinical Evaluative Sciences, Toronto, Canada.
Vaccine. 2008 Nov 5;26(47):6006-12. doi: 10.1016/j.vaccine.2008.08.016. Epub 2008 Aug 30.
Varicella vaccines have been available for private purchase in Canada since 1998. Ontario introduced publicly funded varicella vaccination in 2004. We assessed the effects of private availability of varicella vaccines and subsequent implementation of a publicly funded vaccination program on varicella-related hospitalizations, emergency department (ED) use, and visits to physicians' offices in Ontario. Rates of hospitalizations, ED use, and office visits decreased 53% (95% CI, 48-58%), 43% (95% CI, 41-44%), and 45% (95% CI, 44-45%) after publicly funded vaccination, compared to only 9% (95% CI, 4-14%), 23% (95% CI, 22-24%), and 29% (95% CI, 28-29%) after private availability. Varicella vaccination is effective at reducing varicella-related health care use, with benefits extending beyond those who receive the vaccine. Publicly funded vaccination programs may be more effective than private vaccine availability.
自1998年起，水痘疫苗在加拿大可自行购买。安大略省于2004年推出了由公共资金资助的水痘疫苗接种项目。我们评估了水痘疫苗的私人可购买情况以及随后实施的公共资金资助疫苗接种项目对安大略省水痘相关住院率、急诊科（ED）就诊率和医生办公室就诊率的影响。与仅在私人可购买疫苗后住院率、ED就诊率和门诊就诊率分别下降9%（95%置信区间，4%-14%）、23%（95%置信区间，22%-24%）和29%（95%置信区间，28%-29%）相比，在公共资金资助疫苗接种后，住院率、ED就诊率和门诊就诊率分别下降了53%（95%置信区间，48%-58%）、43%（95%置信区间，41%-44%）和45%（95%置信区间，44%-45%）。水痘疫苗接种在减少水痘相关医疗保健使用方面是有效的，其益处不仅限于接种疫苗的人群。公共资金资助的疫苗接种项目可能比私人可购买疫苗更有效。
