衰老与先天免疫。

Aging and innate immunity.

作者信息

Solana Rafael, Pawelec Graham, Tarazona Raquel

机构信息

Department of Cellular Biology, Physiology, and Immunology, University of Córdoba, E-14004 Córdoba, Spain.

出版信息

Immunity. 2006 May;24(5):491-4. doi: 10.1016/j.immuni.2006.05.003.

DOI:10.1016/j.immuni.2006.05.003

PMID:16713963

Abstract

Adaptive immunity undergoes severe deterioration with age and represents the main problem in the elderly. However, evidence accumulated over the last decade supports the hypothesis that aging also has a profound impact on innate immunity, which in turn markedly impacts the health and longevity of older people.

摘要

适应性免疫会随着年龄的增长而严重衰退，这是老年人面临的主要问题。然而，过去十年积累的证据支持了这样一种假说，即衰老也会对固有免疫产生深远影响，而这反过来又会显著影响老年人的健康和寿命。