Schriner R W, Nada A K, Lie J T, Wilhelm M P, Sterioff S, Donadio J V
Division of Thoracic Diseases, Mayo Clinic, Rochester, MN 55905.
Mayo Clin Proc. 1991 Feb;66(2):183-6. doi: 10.1016/s0025-6196(12)60491-1.
Abdominal pain, oligoarthritis, macular skin rash, and urine sediment with more than 100 erythrocytes per high-power field and proteinuria developed in a renal transplant recipient who had no prior history of an underlying connective tissue disease. A polyarteritis-type necrotizing vasculitis was detected in the small bowel mesentery. A search for other etiologic factors revealed none. This case demonstrates that de novo vasculitis can develop in renal transplant recipients despite adequate immunosuppressive regimens and may respond to increased dosages of corticosteroids.
一名既往无潜在结缔组织病病史的肾移植受者出现腹痛、少关节炎、斑丘疹,且尿沉渣每高倍视野红细胞超过100个并伴有蛋白尿。在小肠系膜中检测到一种多动脉炎型坏死性血管炎。未发现其他病因。该病例表明,尽管采用了充分的免疫抑制方案,肾移植受者仍可能发生新发血管炎,且可能对增加剂量的皮质类固醇有反应。