Rothenberg R J
Am J Med. 1985 Nov;79(5):629-32. doi: 10.1016/0002-9343(85)90061-0.
Dementia developed in a renal transplant recipient who was receiving prednisone (15 mg per day) and azathioprine (50 mg per day). Cerebral computed axial tomography showed multiple areas of infarction. Cerebral angiography demonstrated bilateral vessel changes suggestive of diffuse vasculitis. A search for other causes of vasculitis revealed none. This case demonstrates that isolated angiitis of the brain may develop and progress despite medication capable of suppressing rejection of a transplanted kidney.
一名正在接受泼尼松（每日15毫克）和硫唑嘌呤（每日50毫克）治疗的肾移植受者出现了痴呆症状。脑部计算机断层扫描显示有多个梗死区域。脑血管造影显示双侧血管改变，提示弥漫性血管炎。对血管炎的其他病因进行排查未发现异常。该病例表明，尽管使用了能够抑制移植肾排斥反应的药物，但孤立性脑动脉炎仍可能发生并进展。
