De Sole G, Giese J, Keita F M, Remme J
Onchocerciasis Control Programme in West Africa, Ouagadougou, Burkina Faso.
Acta Trop. 1991 Jan;48(3):203-13. doi: 10.1016/0001-706x(91)90048-o.
Detailed epidemiological mapping of three isolated foci of hyperendemic blinding onchocerciasis was undertaken in three West African countries as part of community trials of ivermectin, a new microfilaricide for the treatment of human onchocerciasis. The results show that the geographical distribution of the prevalence and intensity of onchocerciasis infection in the community can be very different from what was expected on the basis of demographic and entomological information. The technique of detailed epidemiological mapping is an important tool for the identification of target populations for large scale ivermectin treatment of onchocerciasis. It is being used extensively in the Onchocerciasis Control Programme in West Africa.
作为治疗人类盘尾丝虫病的新型杀微丝蚴药伊维菌素社区试验的一部分,在三个西非国家对三个盘尾丝虫病高度流行致盲孤立病灶进行了详细的流行病学测绘。结果表明,社区中盘尾丝虫病感染的患病率和感染强度的地理分布可能与基于人口统计学和昆虫学信息的预期有很大差异。详细的流行病学测绘技术是确定大规模伊维菌素治疗盘尾丝虫病目标人群的重要工具。它正在西非盘尾丝虫病控制计划中广泛应用。