De Sole G, Baker R, Dadzie K Y, Giese J, Guillet P, Keita F M, Remme J
Onchocerciasis Control Programme, Ouagadougou, Burkina Faso, West Africa.
Bull World Health Organ. 1991;69(6):689-98.
The Onchocerciasis Control Programme in West Africa recently extended its operation to Guinea, Guinea-Bissau, the western part of Mali, Senegal and Sierra Leone. To estimate the number of people infected and blinded by the disease and to determine its distribution and severity in the extension area, 215 villages were selected, using a stratified random sampling procedure, and surveyed. All the relevant entomological information available at the time was used in the sampling procedure and in the selection of 92 non-representative villages that were surveyed to confirm the findings. In addition, the populations of 608 villages were examined to map out in detail the distribution of onchocerciasis in the areas at a high risk of onchocercal blindness. The study estimated that 1,475,367 people were infected and 23,728 were blinded from onchocerciasis out of a rural population of 4,464,183. The northern and western part of the study area and the lower Niger basin presented a low or no risk of onchocercal blindness. The upper Niger basin, the south-central part of Sierra Leone, and three small foci in the Gambia, Bakoye, and lower Niger river basins were areas with a high risk of onchocercal blindness. The other parts of the study area presented a medium risk of onchocercal blindness. By detecting the communities at risk of onchocercal disease this study permits the selection of populations for disease control based on mass distribution of ivermectin, a microfilaricide.
西非盘尾丝虫病控制计划最近将其业务扩展到几内亚、几内亚比绍、马里西部、塞内加尔和塞拉利昂。为了估计感染该疾病并致盲的人数，并确定其在扩展区域的分布和严重程度，采用分层随机抽样程序选取了215个村庄进行调查。在抽样过程以及挑选用于确认调查结果的92个非代表性村庄时，使用了当时所有可用的相关昆虫学信息。此外，还对608个村庄的人口进行了检查，以详细绘制盘尾丝虫病在盘尾丝虫性盲症高风险地区的分布情况。该研究估计，在4464183人的农村人口中，有1475367人感染了盘尾丝虫病，23728人因盘尾丝虫病而失明。研究区域的北部和西部以及尼日尔河下游流域盘尾丝虫性盲症的风险较低或没有风险。尼日尔河上游流域、塞拉利昂中南部以及冈比亚、巴科耶河和尼日尔河下游流域的三个小疫源地是盘尾丝虫性盲症高风险地区。研究区域的其他部分盘尾丝虫性盲症风险中等。通过检测有盘尾丝虫病风险的社区，这项研究有助于根据微丝蚴杀虫剂伊维菌素的大规模分发来选择需要疾病控制的人群。
