Panasiti V, Devirgiliis V, Borroni R G, Spataro A, Melis L, Petrella M C, Pala S
Department of Dermatology, University of Rome La Sapienza Viale del Policlinico, 155 00161 Rome, Italy.
J Infect. 2007 Feb;54(2):e55-7. doi: 10.1016/j.jinf.2006.03.036. Epub 2006 May 22.
Herpes simplex virus type 2 (HSV-2) infection was one of the first opportunistic infections identified among patients with AIDS. In the literature there are many data suggesting that the natural history of HSV-2 infection is altered in HIV-HSV-2 co-infected patients. Furthermore, a relationship between HIV seropositivity and HBV infection because of their analogous way of transmission is also described. We report the case of a 37-year-old patient who suffered from multiple painful ulcerative lesions of the perianal region. Laboratory examination showed positivity for HIV and HBV infections. In HIV-positive patients perianal HSV-2 can have atypical manifestations, especially if co-infection by Candida albicans occurs.
2型单纯疱疹病毒（HSV-2）感染是最早在艾滋病患者中发现的机会性感染之一。文献中有许多数据表明，HIV-HSV-2合并感染患者中HSV-2感染的自然病程会发生改变。此外，还描述了由于HIV血清阳性与HBV感染传播方式类似，二者之间存在关联。我们报告了一例37岁患者，其肛周区域出现多处疼痛性溃疡性病变。实验室检查显示HIV和HBV感染呈阳性。在HIV阳性患者中，肛周HSV-2可能有非典型表现，尤其是在发生白色念珠菌合并感染时。
