Archambeaud-Mouveroux F, Lopez S, Combes C, Lassandre S, Amaniou M, Teissier M-P, Galinat S
Service de Médecine Interne B-d'Endocrinologie, Hôpital du Cluzeau, 23, avenue Dominique-Larrey, 87042 Limoges, France.
Rev Med Interne. 2006 Jul;27(7):573-4. doi: 10.1016/j.revmed.2006.02.013. Epub 2006 May 3.
Rhabdomyolysis with fibrate have been reported when fibrate are associated with statin or during renal insufficiency or hypothyroidism.
We describe one patient with diabetes mellitus treated by fenofibrate monotherapy since several years; 48 h after gliclazide therapy was introduced, rhabdomyolysis occurred.
Responsibilities of deshydratation and / or drug interaction with gliclazide. are discussed.
当贝特类药物与他汀类药物联用、或在肾功能不全或甲状腺功能减退期间，已有关于贝特类药物导致横纹肌溶解的报道。
我们描述了一名糖尿病患者，该患者多年来一直接受非诺贝特单药治疗；在引入格列齐特治疗48小时后，发生了横纹肌溶解。
讨论了脱水和/或与格列齐特的药物相互作用的责任。
