Andersen Per
Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Norway.
Prog Neurobiol. 2006 Feb-Apr;78(3-5):264-71. doi: 10.1016/j.pneurobio.2006.02.005. Epub 2006 May 23.
After scientific successes in the study of synaptic activation and inhibition of motoneurons and unraveling mechanisms underlying presynaptic inhibition, Sir John Eccles was interested in studying synaptic mechanisms governing the activity of neurons in the brain stem, cerebellum, and various cortical areas. In this new arena, his group discovered several principles, which have later been shown to generalize across brain structures and have substantial functional significance. Among these were the first identification and location of inhibitory synapses in the cerebral cortex and recurrent inhibitory systems in the hippocampus, cerebellum, and thalamus.
在对运动神经元的突触激活与抑制以及揭示突触前抑制潜在机制的研究取得科学成果之后，约翰·埃克尔斯爵士对研究控制脑干、小脑及各个皮质区域神经元活动的突触机制产生了兴趣。在这个新领域中，他的团队发现了若干原理，这些原理后来被证明可推广至整个脑结构且具有重大的功能意义。其中包括首次在大脑皮层中识别并定位抑制性突触，以及在海马体、小脑和丘脑发现的反馈抑制系统。
