McCue M D
Department of Biology, University of Arkansas, 601 Science Engineering, Fayetteville, AR 72701, USA.
Comp Biochem Physiol A Mol Integr Physiol. 2006 Aug;144(4):381-94. doi: 10.1016/j.cbpa.2006.03.011. Epub 2006 Mar 30.
Specific dynamic action (SDA) is the term used to refer to the increased metabolic expenditure that occurs in postprandial animals. Postprandial increases in metabolism were first documented in animals over two hundred years ago, and have since been observed in every species thus far examined. Ironically, the ubiquity of this physiological response to feeding understates its complex nature. This review is designed to summarize both classical and modern hypotheses regarding the causality of SDA as well as to review important findings from the past century of scientific research into SDA. A secondary aim of this work is to emphasize the importance of carefully designed experiments and systematic hypothesis testing to make more rapid progress in understanding the physiological processes that contribute to SDA. I also identify three areas in SDA research that deserve more detailed investigation. The first area is identification of the causality of SDA in 'model' organisms. The second area is characterization of SDA responses in novel species. The third area is exploration of the ecological and potential evolutionary significance of SDA in energy budgets of animals.
特殊动力作用（SDA）是用于指代餐后动物代谢消耗增加的术语。餐后代谢增加早在两百多年前就已在动物身上得到记录，并且迄今为止在已研究的每个物种中都有观察到。具有讽刺意味的是，这种对进食的生理反应的普遍性掩盖了其复杂的本质。本综述旨在总结关于SDA因果关系的经典和现代假说，并回顾过去一个世纪对SDA进行科学研究的重要发现。这项工作的第二个目标是强调精心设计的实验和系统的假说检验对于在理解导致SDA的生理过程方面取得更快进展的重要性。我还确定了SDA研究中值得更详细研究的三个领域。第一个领域是确定“模式”生物中SDA的因果关系。第二个领域是表征新物种中的SDA反应。第三个领域是探索SDA在动物能量预算中的生态和潜在进化意义。
