通过转化能力筛选出的猴病毒40温度敏感突变体。
Temperature-sensitive mutants of simian virus 40 selected by transforming ability.
作者信息
Yamaguchi N, Kuchino T
出版信息
J Virol. 1975 Jun;15(6):1297-301. doi: 10.1128/JVI.15.6.1297-1301.1975.
Abstract
Eight temperature-sensitive mutants of simian virus 40 which transform rat cells at 32.5 C but not at 38.5 C have been isolated. All the mutants were also temperature sensitive for replication in African green monkey kidney cells and five of them were classified into a single complementation group. No mutant incapable of transforming rat cells at either temperature was isolated.
摘要
已分离出猿猴病毒40的八个温度敏感突变体，这些突变体在32.5℃时可转化大鼠细胞，但在38.5℃时则不能。所有突变体在非洲绿猴肾细胞中的复制也对温度敏感，其中五个被归为一个互补群。未分离出在任何一个温度下都不能转化大鼠细胞的突变体。
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