Hide G, Tait A
Wellcome Unit of Molecular Parasitology, University of Glasgow, Scotland.
Experientia. 1991 Feb 15;47(2):128-42. doi: 10.1007/BF01945413.
The explosion of new techniques, made available by the rapid advance in molecular biology, has provided a battery of novel approaches and technology which can be applied to more practical issues such as the epidemiology of parasites. In this review, we discuss the ways in which this new field of molecular epidemiology has contributed to and corroborated our existing knowledge of parasite epidemiology. Similar epidemiological questions can be asked about many different types of parasites and, using detailed examples such as the African trypanosomes and the Leishmania parasites, we discuss the techniques and the methodologies that have been or could be employed to solve many of these epidemiological problems.
分子生物学的迅速发展带来了新技术的激增,提供了一系列新颖的方法和技术,可应用于诸如寄生虫流行病学等更实际的问题。在本综述中,我们讨论了这个分子流行病学新领域对我们现有寄生虫流行病学知识的贡献方式以及对其的佐证。关于许多不同类型的寄生虫都可以提出类似的流行病学问题,我们以非洲锥虫和利什曼原虫等详细例子,讨论了已经或可用于解决许多此类流行病学问题的技术和方法。