França Danilo Alves de, Langoni Helio
Universidade Estadual Paulista, Departamento de Produção Animal e Medicina Veterinária Preventiva, Botucatu, São Paulo, Brazil.
Rev Inst Med Trop Sao Paulo. 2025 Mar 3;67:e17. doi: 10.1590/S1678-9946202567017. eCollection 2025.
This review explores the landscape of prevalent zoonotic diseases in Sao Paulo State, Brazil, focusing on the role of bats as reservoirs and the application of molecular biology in the diagnosis. The zoonoses covered include visceral and cutaneous leishmaniasis, Chagas disease, toxoplasmosis, bartonellosis, Q fever, Brazilian spotted fever, and leptospirosis. Molecular techniques can improve public health responses by accurately identifying pathogens and tracking their transmission dynamics in populations, thus enhancing early detection, characterization of strains, and monitoring of disease outbreaks. By elucidating the epidemiology and molecular aspects of zoonoses associated with bats in Sao Paulo State, we highlight the importance of integrated surveillance systems and multidisciplinary approaches to effectively manage and prevent these diseases.
本综述探讨了巴西圣保罗州常见人畜共患病的情况，重点关注蝙蝠作为宿主的作用以及分子生物学在诊断中的应用。所涵盖的人畜共患病包括内脏利什曼病和皮肤利什曼病、恰加斯病、弓形虫病、巴尔通体病、Q热、巴西斑疹热和钩端螺旋体病。分子技术可以通过准确识别病原体并追踪其在人群中的传播动态来改善公共卫生应对措施，从而加强早期检测、菌株特征分析和疾病暴发监测。通过阐明圣保罗州与蝙蝠相关的人畜共患病的流行病学和分子方面，我们强调了综合监测系统和多学科方法对有效管理和预防这些疾病的重要性。
