Nordvik Monica K, Liljeros Fredrik
Department of Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Sex Transm Dis. 2006 Jun;33(6):342-9. doi: 10.1097/01.olq.0000194601.25488.b8.
To investigate the impact of the number of sexual encounters involving intercourse in combination with the number of sexual partners on the transmission dynamics of sexually transmitted infections (STIs).
A statistical model is used for predicting the basic reproductive rate, R(0), which takes both the number of sexual partners and the number of sexual encounters involving intercourse per partner into consideration. The model is then applied to Swedish survey data that includes data on the number of partners over the course of 1 year, as well as the number of encounters per partner during this time.
The number of sexual encounters involving intercourse in combination with the number of sexual partners affects the number of secondary infections in a nonlinear way. The basic reproductive rate, R(0), is lower when the heterogeneity in number of encounters is modeled than when homogeneity is assumed.
The results indicate that it is possible that individuals who have a large number of partners may not, as is often assumed, be the only ones to play a central role as spreaders of STIs. Individuals who have a large number of sexual encounters involving intercourse per partner and have several (but not necessarily a very large number of) partners may also play a significant role in the transmission of STIs.
研究涉及性交的性接触次数与性伴侣数量相结合对性传播感染(STIs)传播动态的影响。
使用统计模型预测基本繁殖率R(0),该模型同时考虑了性伴侣数量和每个伴侣涉及性交的性接触次数。然后将该模型应用于瑞典的调查数据,这些数据包括1年内性伴侣数量的数据以及这段时间内每个伴侣的接触次数。
涉及性交的性接触次数与性伴侣数量相结合以非线性方式影响二代感染数量。当对接触次数的异质性进行建模时,基本繁殖率R(0)低于假设同质性时的情况。
结果表明,拥有大量性伴侣的个体可能并非如通常所认为的那样,是性传播感染传播者中唯一发挥核心作用的群体。每个伴侣有大量涉及性交的性接触且有几个(但不一定非常多)性伴侣的个体在性传播感染的传播中也可能发挥重要作用。