Osada Hideo, Mori Kentaro, Yamamoto Takuji, Nakao Yasuaki, Wada Ryo, Maeda Minoru
Department of Neurosurgery, Juntendo University, Shizuoka Hospital, Japan.
Neurol Med Chir (Tokyo). 2006 May;46(5):251-3. doi: 10.2176/nmc.46.251.
A 53-year-old man presented with a choroid plexus carcinoma in the body of the right lateral ventricle manifesting as gait disturbance due to left mild hemiparesis and papilledema. Subtotal removal of the tumor was performed. Histological examination revealed well-differentiated papillary adenocarcinoma. Immunohistochemical examination showed intense reactivity for carbohydrate antigen 19-9 (CA19-9). The serum level of CA19-9 was significantly high, but decreased rapidly after radiation therapy. Systemic examinations found no malignancy in other organs. This second case of choroid plexus carcinoma producing CA19-9 indicates that CA19-9 may be a useful marker of choroid plexus carcinoma.
一名53岁男性因右侧脑室体部脉络丛癌就诊，表现为左侧轻度偏瘫和视乳头水肿导致的步态障碍。对肿瘤进行了次全切除。组织学检查显示为高分化乳头状腺癌。免疫组化检查显示对糖类抗原19-9（CA19-9）有强烈反应。CA19-9的血清水平显著升高，但放疗后迅速下降。全身检查未发现其他器官有恶性肿瘤。这例产生CA19-9的脉络丛癌的第二个病例表明，CA19-9可能是脉络丛癌的一个有用标志物。
