Department of Radiation Oncology, Soonchunhyang University College of Medicine, Cheonan, Republic of Korea.
Department of Neurosurgery, Soonchunhyang University College of Medicine, Cheonan, Republic of Korea.
J Med Case Rep. 2021 May 23;15(1):286. doi: 10.1186/s13256-021-02887-2.
Choroid plexus carcinoma is an intraventricular neoplasm originating from the choroid plexus epithelium and is of rare occurrence in adults. However, owing to the low prevalence of choroid plexus carcinoma, there is very limited information about the disease entity and treatment. Here we report a rare case of choroid plexus carcinoma in an adult patient.
A 46-year-old South Korean (East Asian) male presented with low back pain, headache, and diplopia. Magnetic resonance imaging demonstrated enhancing mass lesion in the left trigone, cerebellar with leptomeningeal spread. Surgery was performed via left parietal craniotomy, and the lesion was histologically confirmed to be choroid plexus carcinoma. The patient received adjuvant craniospinal irradiation for remnant mass and leptomeningeal spread. Magnetic resonance imaging performed immediately after completion of the treatment revealed a partial decrease in the size of the tumor. However, the patient expired died as a result of acute respiratory distress syndrome before follow-up of long-term outcome.
Choroid plexus carcinoma with leptomeningeal spread in adults is very important for rapid diagnosis and treatment. In the case of the presence of leptomeningeal spread, craniospinal irradiation can be considered as a treatment method, but may have serious complications. Hence, the technique should be applied with care.
脉络丛癌是一种起源于脉络丛上皮的脑室肿瘤，在成人中罕见。然而，由于脉络丛癌的患病率很低，关于该疾病实体和治疗的信息非常有限。在此，我们报告一例成人脉络丛癌的罕见病例。
一名 46 岁的韩国（东亚）男性，表现为腰痛、头痛和复视。磁共振成像显示左侧三角区、小脑伴软脑膜播散的增强肿块病变。通过左顶骨开颅手术进行了手术，病变的组织学证实为脉络丛癌。患者接受了残余肿块和软脑膜播散的辅助颅脊髓放疗。治疗完成后立即进行的磁共振成像显示肿瘤大小部分缩小。然而，由于急性呼吸窘迫综合征，患者在长期结果随访之前死亡。
成人伴软脑膜播散的脉络丛癌需要快速诊断和治疗。如果存在软脑膜播散，颅脊髓放疗可以被认为是一种治疗方法，但可能会有严重的并发症。因此，该技术的应用需要谨慎。
