遗传学作为改善癌症治疗效果的工具：伦理与政策

Genetics as a tool to improve cancer outcomes: ethics and policy.

作者信息

Burke Wylie, Press Nancy

机构信息

Department of Medical History and Ethics, University of Washington, BOX 357120, 1959 North East Pacific, Room A204, Seattle, Washington 98195-7120, USA.

出版信息

Nat Rev Cancer. 2006 Jun;6(6):476-82. doi: 10.1038/nrc1890.

DOI:10.1038/nrc1890

PMID:16723994

Abstract

Genetic research is rapidly increasing the opportunities for the detection of inherited cancer risk. Clinicians and policy makers must ensure the adequate evaluation of the benefits and harms of this new area of practice, address the challenges of family-based detection of individuals at risk and develop practice guidelines and educational strategies that are responsive to rapidly changing knowledge. When the benefits of testing are well established, efforts must also be made to ensure access to genetic services for all who can benefit.

摘要

基因研究正在迅速增加检测遗传性癌症风险的机会。临床医生和政策制定者必须确保对这一新兴实践领域的利弊进行充分评估，应对基于家庭检测个体风险的挑战，并制定能够响应快速变化知识的实践指南和教育策略。当检测的益处得到充分证实时，还必须努力确保所有能够受益的人都能获得基因服务。