耳叶乌头根中的二萜生物碱

Diterpenoid alkaloids from the roots of Aconitum cochleare.

作者信息

Meriçli A H, Süzgeç S, Bitiş L, Meriçli F, Ozçelik H, Zapp J, Becker H

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, Beyazit, Turkey.

出版信息

Pharmazie. 2006 May;61(5):483-5.

PMID:16724552

Abstract

From the roots of Aconitum cochleare Woroschin, collected in Turkey, a new diterpenoid alkaloid named acochlearine has been isolated along with the known diterpenoid alkaloids talatisamine, 14-O-acetyltalatisamine, senbusine C and condelphine. The structure for acochlearine was established on the basis of 1H, 13C, DEPT, homonuclear 1H COSY, NOESY, HSQC and HMBC NMR studies.

摘要

从采集于土耳其的耳蜗乌头（Aconitum cochleare Woroschin）的根中，分离出了一种名为耳蜗碱的新二萜生物碱，以及已知的二萜生物碱塔拉胺、14-O-乙酰塔拉胺、senbusine C和coniine。基于1H、13C、DEPT、同核1H COSY、NOESY、HSQC和HMBC NMR研究确定了耳蜗碱的结构。