Bodine A B, Alberty C F, Buck C S, Richardson M E, Wright R E
Department of Dairy Science Clemson University Clemson, SC 29631 USA.
Theriogenology. 1981 Aug;16(2):201-6. doi: 10.1016/0093-691x(81)90102-3.
A pregnant Holstein cow was experimentally inoculated with bovine parvovirus. Approximately five weeks after the last of three injections, the animal aborted a fetus which showed signs of mummification. Virus particles similar to bovine parvovirus were identified by electron microscopy from fetal lung tissue and intestinal contents. Five months after the abortion, the experimental animal died of a corynebacterial metritis and septicemia. Immunofluorescence tests were performed on representative tissues obtained at necropsy. Of all tissues examined only the uterus showed a positive response to the immunofluorescence assay, indicating that the viral antigen persisted in the uterine environment long after its elimination from the systemic circulation.
一头怀孕的荷斯坦奶牛被实验性接种了牛细小病毒。在三次注射中的最后一次注射大约五周后，这头动物流产了一头呈现木乃伊化迹象的胎儿。通过电子显微镜从胎儿肺组织和肠道内容物中鉴定出了与牛细小病毒相似的病毒颗粒。流产五个月后，这头实验动物死于棒状杆菌性子宫炎和败血症。对尸检时获取的代表性组织进行了免疫荧光检测。在所有检查的组织中，只有子宫对免疫荧光测定呈阳性反应，这表明病毒抗原在从体循环中清除后很长时间仍在子宫环境中持续存在。
