Woods G L, Ginther O J
Department of Veterinary Science, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Theriogenology. 1983 Sep;20(3):347-55. doi: 10.1016/0093-691x(83)90068-7.
The efficacy of an equine pituitary extract for induction of multiple ovulations during the ovulatory season was studied in 112 horse mares in four experiments. Combined for all experiments, 70% of the mares (78/112) had multiple ovulations for an average of 3.0 ovulations per mare. The interval between first and last ovulation was decreased (P<0.01) when human chorionic gonadotropin (hCG) was included in the treatment regimen (0.0+/-0.0 versus 1.6+/-0.4 days). Ovulation rate was lower (P<0.01) when extract treatment was initiated at day 19 (1.3+/-0.2) than when initiated at day 15 post-ovulation (2.9+/-0.5). Initiation of extract treatment at day 11 was as effective as initiation at day 15, with or without an injection of prostaglandin F(2alpha) on the first day of extract treatment. Increasing the dose of extract from 750 to 1500 or 2250 units per day did not significantly increase the ovulatory response.
在四项实验中，对112匹母马研究了马垂体提取物在排卵季节诱导多次排卵的功效。综合所有实验，70%的母马（78/112）出现多次排卵，每匹母马平均排卵3.0次。当治疗方案中包含人绒毛膜促性腺激素（hCG）时，首次排卵与末次排卵之间的间隔缩短（P<0.01）（0.0±0.0天对1.6±0.4天）。与排卵后第15天开始提取物治疗相比，在第19天开始提取物治疗时排卵率较低（P<0.01）（1.3±0.2对2.9±0.5）。在第11天开始提取物治疗与在第15天开始一样有效，无论在提取物治疗第一天是否注射前列腺素F（2α）。将提取物剂量从每天750单位增加到1500或2250单位并未显著增加排卵反应。
