Sanfilippo J S, Liu Y K
Department of Obstetrics and Gynecology, University of Louisville, School of Medicine, Kentucky.
Int J Fertil. 1991 Jan-Feb;36(1):36-8.
An oligomenorrheic infertile patient with evidence of vitamin B12 (cobalamin) deficiency is described. Treatment consisted of clomiphene citrate, human chorionic gonadotropin (hCG), conjugated estrogens, dexamethasone, and ferrous sulfate. Pregnancy occurred after 1,000 micrograms of vitamin B12 was added to the treatment regimen. We believe the patient's infertility was in part related to the megaloblastic anemia. A possible correlation between vitamin B12 deficiency and failure to ovulate is presented.
本文描述了一名月经过少的不孕患者，有维生素B12（钴胺素）缺乏的证据。治疗包括枸橼酸氯米芬、人绒毛膜促性腺激素（hCG）、结合雌激素、地塞米松和硫酸亚铁。在治疗方案中添加1000微克维生素B12后患者怀孕。我们认为该患者的不孕部分与巨幼细胞贫血有关。本文还提出了维生素B12缺乏与排卵障碍之间可能存在的关联。
