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[镇痛药对雄性仔猪去势的影响]

[Effect of analgesics on the castration of male piglets].

作者信息

Zöls Susanne, Ritzmann Mathias, Heinritzi Karl

机构信息

Klinik für Schweine der Ludwig-Maximilians-Universität München.

出版信息

Berl Munch Tierarztl Wochenschr. 2006 May-Jun;119(5-6):193-6.

Abstract

According to the current German animal welfare law, male piglets may be surgical castrated without anaesthesia up to four weeks of life. This surgical procedure is painful during and also after the operation, for newborn animals as well as for adults. This study was aimed to investigate the impact of preoperative application of analgesics (Meloxicam) on the postoperative castration - pain of four to six days old male piglets. In this investigation all animals were randomly distributed in three groups:the first one was only immobilized but had no surgery, the second one was castrated without analgesics, and the third group was castrated after application of Meloxicam. Blood samples were taken immediately before immobilization, castration or application of the analgesic as well as one, four and 28 hours afterwards to determine Cortisol-concentration in the blood serum and, via this stress-marker, to indirectly evaluate the postoperative und possible intraoperative castration-pain. As a result all piglets castrated without preoperative application of Meloxicam showed significantly increased Cortisol-concentration one and four hours after castration. In contrast, piglets castrated with analgesics resulted in no significant increase during the entire experiment.

摘要

根据现行德国动物福利法,雄性仔猪在出生四周内可在不使用麻醉的情况下进行手术阉割。这种手术操作在术中及术后对新生动物和成年动物来说都是痛苦的。本研究旨在调查术前应用镇痛药(美洛昔康)对4至6日龄雄性仔猪术后阉割疼痛的影响。在这项研究中,所有动物被随机分为三组:第一组仅进行固定但不做手术,第二组不使用镇痛药进行阉割,第三组在应用美洛昔康后进行阉割。在固定、阉割或应用镇痛药之前以及之后1小时、4小时和28小时采集血样,以测定血清中的皮质醇浓度,并通过这个应激指标间接评估术后以及可能的术中阉割疼痛。结果,所有未在术前应用美洛昔康进行阉割的仔猪在阉割后1小时和4小时血清皮质醇浓度显著升高。相比之下,使用镇痛药进行阉割的仔猪在整个实验过程中皮质醇浓度没有显著升高。

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