Bower Carol
Western Australian Birth Defects Registry, Women's and Children's Health Service, Western Australia, Australia.
Congenit Anom (Kyoto). 2006 Jun;46(2):118-21. doi: 10.1111/j.1741-4520.2006.00112.x.
This paper reviews the role of the Western Australian Birth Defects Registry in the primary prevention of neural tube defects. The Registry provides complete and up-to-date information on all neural tube defects (NTD), including terminations of pregnancy. These data have been used to determine a baseline rate of NTD and to monitor trends in NTD over time, when health promotion of folic acid supplement use and voluntary fortification of food with folate were introduced. The register has also been used to investigate NTD in special populations (Indigenous infants in Australia) and as a sampling frame for case control studies. The data derived from these studies have been used to assist in assessing whether mandatory food fortification in Australia is indicated to prevent NTD.
本文回顾了西澳大利亚出生缺陷登记处在神经管缺陷一级预防中的作用。该登记处提供了关于所有神经管缺陷（NTD）的完整且最新的信息，包括妊娠终止情况。这些数据已被用于确定神经管缺陷的基线率，并在引入叶酸补充剂使用的健康促进措施和食品自愿添加叶酸时，监测随时间推移神经管缺陷的趋势。该登记处还被用于调查特殊人群（澳大利亚原住民婴儿）中的神经管缺陷，并作为病例对照研究的抽样框架。这些研究得出的数据已被用于协助评估澳大利亚是否需要进行强制性食品强化以预防神经管缺陷。
