Letsas Konstantinos P, Filippatos Gerasimos S, Delimpasi Sossana, Spanakis Nicholas, Kounas Stavros P, Efremidis Michalis, Tsakris Athanassios, Kardaras Fotios
Second Department of Cardiology, Evangelismos General Hospital of Athens, 10676 Athens, Greece.
J Infect. 2007 Feb;54(2):e75-7. doi: 10.1016/j.jinf.2006.04.006. Epub 2006 Jun 2.
We report the case of a 17-year-old male who was admitted to the emergency department in cardiogenic shock and multiorgan failure due to fulminant myocarditis. The following days the patient developed anemia, thrombocytopenia, and hepatosplenomegaly. Bone marrow examination showed many mature histiocytes with active hemophagocytosis. Nested reverse transcriptase-PCR molecular analysis of blood samples and sequencing of the amplified alleles confirmed enteroviral infection. Our patient was treated with inotropic agents and immunoglobulin, and recovered completely. This is the first report that documents concomitant presentation of fulminant myocarditis and hemophagocytic syndrome due to enteroviral infection.
我们报告了一例17岁男性患者，因暴发性心肌炎导致心源性休克和多器官功能衰竭而被收入急诊科。在接下来的几天里，患者出现贫血、血小板减少和肝脾肿大。骨髓检查显示许多成熟组织细胞伴有活跃的噬血细胞现象。对血样进行巢式逆转录酶 - PCR分子分析及对扩增等位基因进行测序，证实为肠道病毒感染。我们的患者接受了强心剂和免疫球蛋白治疗，并完全康复。这是第一份记录肠道病毒感染导致暴发性心肌炎和噬血细胞综合征同时出现的报告。
