Didelot A, Kremer S, Schmitt E, Maillard L, Gibot S, Cravoisi A, Vespignani H, Bracard S, Picard L
Service de Neurologie, Hôpital Central, 29 avenue Maréchal de Lattre de Tassigny, 54035 Nancy Cedex.
J Neuroradiol. 2006 Apr;33(2):121-5. doi: 10.1016/s0150-9861(06)77241-8.
We report the MR imaging findings in a 20 year old woman with status epilepticus of more than 3 months duration following an episode of lymphocytic meningitis. Repeated MR examinations showed progressive symmetrical cortical lesions, followed by subcortical and basal ganglia lesions which evolved to cortical laminar necrosis and hemorrhagic necrosis with eventual subcortical cerebral atrophy. This case has similarities with animal status epilepticus models. Biological investigations were all negative. This suggests that the brain lesions may be related to the prolonged status epilepticus.
我们报告了一名20岁女性的磁共振成像(MR)检查结果,该患者在淋巴细胞性脑膜炎发作后出现持续超过3个月的癫痫持续状态。多次MR检查显示,病变呈进行性、对称性累及皮质,随后累及皮质下及基底节区,进而发展为皮质层状坏死和出血性坏死,最终导致皮质下脑萎缩。该病例与动物癫痫持续状态模型有相似之处。各项生物学检查均为阴性。这表明脑损伤可能与癫痫持续状态的持续时间较长有关。